Avian Influenza Optimal Seasonal Vaccination Strategy

Heterologous Humoral Response against H5N1, H7N3, and H9N2 Avian Influenza Viruses after Seasonal Vaccination in a European Elderly Population

Avian influenza viruses are currently one of the main threats to human health in the world. Although there are some screening reports of antibodies against these viruses in humans from Western countries, most of these types of studies are conducted in poultry and market workers of Asian populations. The presence of antibodies against avian influenza viruses was evaluated in an elderly European ...

Vaccination of Chicks with Experimental Newcastle Disease and Avian Influenza Oilemulsion Vaccines by ln Ovo Inoculation

Vaccination Strategy and Optimal Control for Seasonal and H1N1 Influenza Outbreak

During the spring of 2009, a novel H1N1 influenza virus posed a serious threat worldwide. However, seasonal influenza is still a public health concern since each year in the United States it kills 36,000 people, causes more than 200,000 hospitalizations, and infects up to 20% of the population. In this paper, we explore what could happen if both a seasonal influenza and H1N1 outbreak were to co...

Evaluation of In Vitro Cross-Reactivity to Avian H5N1 and Pandemic H1N1 2009 Influenza Following Prime Boost Regimens of Seasonal Influenza Vaccination in Healthy Human Subjects: A Randomised Trial

INTRODUCTION Recent studies have demonstrated that inactivated seasonal influenza vaccines (IIV) may elicit production of heterosubtypic antibodies, which can neutralize avian H5N1 virus in a small proportion of subjects. We hypothesized that prime boost regimens of live and inactivated trivalent seasonal influenza vaccines (LAIV and IIV) would enhance production of heterosubtypic immunity and ...

High coverage of influenza vaccination among healthcare workers can be achieved during heightened awareness of impending threat.

INTRODUCTION As preparation against a possible avian flu pandemic, international and local health authorities have recommended seasonal influenza vaccination for all healthcare workers at geographical risk. This strategy not only reduces "background noise", but also chance of genetic shifts in avian influenza viruses when co-infection occurs. We evaluate the response of healthcare workers, stra...